Cargando…

Correction: Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design

Detalles Bibliográficos
Autores principales:	Peat, Thomas S., Rhodes, David I., Vandegraaff, Nick, Le, Giang, Smith, Jessica A., Clark, Lisa J., Jones, Eric D., Coates, Jonathan A. V., Thienthong, Neeranat, Newman, Janet, Dolezal, Olan, Mulder, Roger, Ryan, John H., Savage, G. Paul, Francis, Craig L., Deadman, John J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Correction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721960/ http://dx.doi.org/10.1371/annotation/eb238f0f-7582-4318-af95-64ac98d3b0be

Ejemplares similares

Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design
por: Peat, Thomas S., et al.
Publicado: (2012)

The Interaction Between Lentiviral Integrase and LEDGF: Structural and Functional Insights
por: Hare, Stephen, et al.
Publicado: (2009)

The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75
por: Zhang, Da-Wei, et al.
Publicado: (2020)

The Lentiviral Integrase Binding Protein LEDGF/p75 and HIV-1 Replication
por: Engelman, Alan, et al.
Publicado: (2008)

LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro
por: Cherepanov, Peter
Publicado: (2007)

Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75
por: Lapaillerie, Delphine, et al.
Publicado: (2021)

Characterization of the HIV-1 integrase chromatin- and LEDGF/p75-binding abilities by mutagenic analysis within the catalytic core domain of integrase
por: Zheng, Yingfeng, et al.
Publicado: (2010)

HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin
por: Astiazaran, Paulina, et al.
Publicado: (2011)

Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage
por: Le Rouzic, Erwann, et al.
Publicado: (2013)

LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV
por: Vranckx, Lenard S., et al.
Publicado: (2016)

A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site
por: Maehigashi, Tatsuya, et al.
Publicado: (2021)

The DINGO dataset: a comprehensive set of data for the SAMPL challenge
por: Newman, Janet, et al.
Publicado: (2011)

An Unusual Helix Turn Helix Motif in the Catalytic Core of HIV-1 Integrase Binds Viral DNA and LEDGF
por: Merad, Hayate, et al.
Publicado: (2009)

Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein
por: Bao, Leyuan, et al.
Publicado: (2017)

Molecular Modeling Study on the Allosteric Inhibition Mechanism of HIV-1 Integrase by LEDGF/p75 Binding Site Inhibitors
por: Xue, Weiwei, et al.
Publicado: (2014)

Efficient transduction of LEDGF/p75 mutant cells by complementary gain-of-function HIV-1 integrase mutant viruses
por: Wang, Hao, et al.
Publicado: (2014)

Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors
por: Singh, Parmit Kumar, et al.
Publicado: (2022)

HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor
por: Wang, Hao, et al.
Publicado: (2012)

Fragment screening for a protein-protein interaction inhibitor to WDR5
por: Dennis, Matthew L., et al.
Publicado: (2019)

Studies on HIV integrase-LEDGF/p75 interaction inhibitory activity of isatine derivative using the alpha screen luminescent proximity assay
por: Selvam, Periyasamy
Publicado: (2012)

The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells
por: Ortiz-Hernandez, Greisha L., et al.
Publicado: (2021)

Multivalency of nucleosome recognition by LEDGF
por: Koutná, Eliška, et al.
Publicado: (2023)

Evaluation of a flavonoid library for inhibition of interaction of HIV-1 integrase with human LEDGF/p75 towards a structure–activity relationship
por: Yin, Zhi-Hui, et al.
Publicado: (2022)

A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75
por: Hare, Stephen, et al.
Publicado: (2009)

A Novel Assay for Screening Inhibitors Targeting HIV Integrase LEDGF/p75 Interaction Based on Ni(2+) Coated Magnetic Agarose Beads
por: Dawei, Zhang, et al.
Publicado: (2016)

Exploring the Chemical Space around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme HPPK
por: Chhabra, Sandeep, et al.
Publicado: (2013)

Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells
por: Levin, Aviad, et al.
Publicado: (2010)

The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity
por: Amadori, Céline, et al.
Publicado: (2017)

Analysis of LEDGF/p75 expression regulation
por: Desfarges, Sébastien, et al.
Publicado: (2009)

Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor
por: Chhabra, Sandeep, et al.
Publicado: (2012)

Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes
por: Eidahl, Jocelyn O., et al.
Publicado: (2013)

LEDGF/p75 Is Required for an Efficient DNA Damage Response
por: Liedtke, Victoria, et al.
Publicado: (2021)

Simian immunodeficiency virus-Vpx as an adjuvant for integrase defective lentiviral vector-based vaccines
por: Blasi, M, et al.
Publicado: (2012)

Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines
por: Negri, Donatella RM, et al.
Publicado: (2012)

HIV-1 IN/Pol recruits LEDGF/p75 into viral particles
por: Desimmie, Belete Ayele, et al.
Publicado: (2015)

The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors of the Human Immunodeficiency Virus Ribonuclease H and Integrase Enzymes
por: Tavis, John E., et al.
Publicado: (2013)

Resistance Mutations outside the Integrase Coding Region Have an Effect on Human Immunodeficiency Virus Replicative Fitness but Do Not Affect Its Susceptibility to Integrase Strand Transfer Inhibitors
por: Weber, Jan, et al.
Publicado: (2013)

Role of PSIP1/LEDGF/p75 in Lentiviral Infectivity and Integration Targeting
por: Marshall, Heather M., et al.
Publicado: (2007)

High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region
por: De Rijck, Jan, et al.
Publicado: (2010)

LEDGF/p75 is critical but not essential for multiple-round HIV 1 replication
por: Schrijvers, RLG, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_fi4otcphdmmc3m6279hll3h2h2