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Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma

BACKGROUND: Burkitt leukemia/lymphoma is a major subtype of aggressive B-cell lymphoma. Biological targeted therapies on this disease need to be further investigated and may help to improve the clinical outcome of the patients. METHODS: This study examined the anti-tumor activity of the histone deac...

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Detalles Bibliográficos
Autores principales: Dong, Li Hua, Cheng, Shu, Zheng, Zhong, Wang, Li, Shen, Yang, Shen, Zhi Xiang, Chen, Sai Juan, Zhao, Wei Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722002/
https://www.ncbi.nlm.nih.gov/pubmed/23866964
http://dx.doi.org/10.1186/1756-8722-6-53