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Clinicopathological correlates and prognostic significance of KRAS mutation status in a pooled prospective cohort of epithelial ovarian cancer

BACKGROUND: Activating KRAS mutations are common in ovarian carcinomas of low histological grade, less advanced clinical stage and mucinous histological subtype, and form part of the distinct molecular alterations associated with type I tumors in the dualistic model of ovarian carcinogenesis. Here,...

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Detalles Bibliográficos
Autores principales: Nodin, Björn, Zendehrokh, Nooreldin, Sundström, Magnus, Jirström, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722044/
https://www.ncbi.nlm.nih.gov/pubmed/23800114
http://dx.doi.org/10.1186/1746-1596-8-106