Overcoming barriers and thresholds – signaling of oligomeric Aβ through the prion protein to Fyn

Evidence has been mounting for an involvement of the prion protein (PrP) in a molecular pathway assumed to play a critical role in the etiology of Alzheimer disease. A currently popular model sees oligomeric amyloid β (oAβ) peptides bind directly to PrP to emanate a signal that causes activation of...

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Detalles Bibliográficos
Autores principales: Wang, Hansen, Ren, Carl He, Gunawardana, C Geeth, Schmitt-Ulms, Gerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722066/
https://www.ncbi.nlm.nih.gov/pubmed/23856335
http://dx.doi.org/10.1186/1750-1326-8-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722066/
https://www.ncbi.nlm.nih.gov/pubmed/23856335
http://dx.doi.org/10.1186/1750-1326-8-24

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