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The emerging role of RNA polymerase I transcription machinery in human malignancy: a clinical perspective
Ribosome biogenesis – the complex and highly coordinated cellular process leading to the production of ribosomes – is strictly dependent on the activity of RNA polymerase I (Pol I) transcriptional machinery. Pol I activity is continually increased in proliferating cells to sustain the increased dema...
Autores principales: | Montanaro, Lorenzo, Treré, Davide, Derenzini, Massimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722134/ https://www.ncbi.nlm.nih.gov/pubmed/23888116 http://dx.doi.org/10.2147/OTT.S36627 |
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