Involvement of the Same TNFR1 Residue in Mendelian and Multifactorial Inflammatory Disorders

OBJECTIVES: TNFRSF1A is involved in an autosomal dominant autoinflammatory disorder called TNFR-associated periodic syndrome (TRAPS). Most TNFRSF1A mutations are missense changes and, apart from those affecting conserved cysteines, their deleterious effect remains often questionable. This is especia...

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Detalles Bibliográficos
Autores principales: Jéru, Isabelle, Charmion, Serge, Cochet, Emmanuelle, Copin, Bruno, Duquesnoy, Philippe, Garcia, Maria Teresa Mitjavila, Le Borgne, Gaëlle, Cathebras, Pascal, Gaillat, Jacques, Karabina, Sonia, Dodé, Catherine, Lohse, Peter, Hentgen, Véronique, Amselem, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722142/
https://www.ncbi.nlm.nih.gov/pubmed/23894535
http://dx.doi.org/10.1371/journal.pone.0069757

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