Cargando…

DNAJB3/HSP-40 Cochaperone Is Downregulated in Obese Humans and Is Restored by Physical Exercise

Obesity is a major risk factor for a myriad of disorders such as insulin resistance and diabetes. The mechanisms underlying these chronic conditions are complex but low grade inflammation and alteration of the endogenous stress defense system are well established. Previous studies indicated that imp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abubaker, Jehad, Tiss, Ali, Abu-Farha, Mohamed, Al-Ghimlas, Fahad, Al-Khairi, Irina, Baturcam, Engin, Cherian, Preethi, Elkum, Naser, Hammad, Maha, John, Jeena, Kavalakatt, Sina, Khadir, Abdelkrim, Warsame, Samia, Dermime, Said, Behbehani, Kazem, Dehbi, Mohammed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722167/ https://www.ncbi.nlm.nih.gov/pubmed/23894433 http://dx.doi.org/10.1371/journal.pone.0069217

Ejemplares similares

DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression
por: Abu-Farha, Mohamed, et al.
Publicado: (2015)

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
por: Abu-Farha, Mohamed, et al.
Publicado: (2013)

Physical Exercise Reduces the Expression of RANTES and Its CCR5 Receptor in the Adipose Tissue of Obese Humans
por: Baturcam, Engin, et al.
Publicado: (2014)

Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
por: Tiss, Ali, et al.
Publicado: (2014)

Association of obesity with down-regulation of heat shock protein 40 expression and evidence that exercise retrieves its normal expression
por: Abubakr, Jehad, et al.
Publicado: (2012)

Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
por: Khadir, Abdelkrim, et al.
Publicado: (2018)

Gender-Specific Association of Oxidative Stress and Inflammation with Cardiovascular Risk Factors in Arab Population
por: Khadir, Abdelkrim, et al.
Publicado: (2015)

Circulating angiopoietin-like protein 8 (betatrophin) association with HsCRP and metabolic syndrome
por: Abu-Farha, Mohamed, et al.
Publicado: (2016)

Overexpression of the cancer-related DUSP1 gene in human obesity and its modulation by physical exercise
por: Khadir, Abdelkrim, et al.
Publicado: (2014)

PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases
por: Khadir, Abdelkrim, et al.
Publicado: (2020)

Soluble Epoxide Hydrolase 2 Expression Is Elevated in Obese Humans and Decreased by Physical Activity
por: Khadir, Abdelkrim, et al.
Publicado: (2020)

Circulating ANGPTL8/Betatrophin Is Increased in Obesity and Reduced after Exercise Training
por: Abu-Farha, Mohamed, et al.
Publicado: (2016)

Higher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance
por: Abu-Farha, Mohamed, et al.
Publicado: (2015)

DUSP1 Is a Potential Marker of Chronic Inflammation in Arabs with Cardiovascular Diseases
por: Khadir, Abdelkrim, et al.
Publicado: (2018)

Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes
por: Khadir, Abdelkrim, et al.
Publicado: (2020)

Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes
por: Kavalakatt, Sina, et al.
Publicado: (2021)

IL-33 is negatively associated with the BMI and confers a protective lipid/metabolic profile in non-diabetic but not diabetic subjects
por: Hasan, Amal, et al.
Publicado: (2014)

Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise
por: Kavalakatt, Sina, et al.
Publicado: (2019)

Circulating levels of urocortin neuropeptides are impaired in children with overweight
por: Kavalakatt, Sina, et al.
Publicado: (2022)

Lack of associations between betatrophin/ANGPTL8 level and C-peptide in type 2 diabetic subjects
por: Abu-Farha, Mohamed, et al.
Publicado: (2015)

Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone
por: Diane, Abdoulaye, et al.
Publicado: (2020)

Gender Differences in Ghrelin Association with Cardiometabolic Risk Factors in Arab Population
por: Abu-Farha, Mohamed, et al.
Publicado: (2014)

Fetuin-a expression profile in mouse and human adipose tissue
por: Khadir, Abdelkrim, et al.
Publicado: (2020)

ANGPTL8/Betatrophin R59W variant is associated with higher glucose level in non-diabetic Arabs living in Kuwaits
por: Abu-Farha, Mohamed, et al.
Publicado: (2016)

Plasma and adipose tissue level of angiopoietin-like 7 (ANGPTL7) are increased in obesity and reduced after physical exercise
por: Abu-Farha, Mohamed, et al.
Publicado: (2017)

Increased expression level of ANGPTL8 in white adipose tissue under acute and chronic cold treatment
por: Arefanian, Hossein, et al.
Publicado: (2021)

Urocortin Neuropeptide Levels Are Impaired in the PBMCs of Overweight Children
por: Kavalakatt, Sina, et al.
Publicado: (2022)

Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension
por: Abu-Farha, Mohamed, et al.
Publicado: (2018)

Fetuin-A levels are increased in the adipose tissue of diabetic obese humans but not in circulation
por: Khadir, Abdelkrim, et al.
Publicado: (2018)

Comprehensive analysis of circulating adipokines and hsCRP association with cardiovascular disease risk factors and metabolic syndrome in Arabs
por: Abu-Farha, Mohamed, et al.
Publicado: (2014)

High adiponectin levels in lean Arab women compared to Asian women
por: Abu-Farha, Mohamed, et al.
Publicado: (2015)

Profiling of Insulin-Like Growth Factor Binding Proteins (IGFBPs) in Obesity and Their Association With Ox-LDL and Hs-CRP in Adolescents
por: Rahman, Abdur, et al.
Publicado: (2021)

Reduced miR-181d level in obesity and its role in lipid metabolism via regulation of ANGPTL3
por: Abu-Farha, Mohamed, et al.
Publicado: (2019)

Increased ANGPTL3, 4 and ANGPTL8/betatrophin expression levels in obesity and T2D
por: Abu-Farha, Mohamed, et al.
Publicado: (2016)

Targeted Metabolomics Analysis on Obstructive Sleep Apnea Patients after Multilevel Sleep Surgery
por: Alterki, Abdulmohsen, et al.
Publicado: (2020)

Elevated expression of the toll like receptors 2 and 4 in obese individuals: its significance for obesity-induced inflammation
por: Ahmad, Rasheed, et al.
Publicado: (2012)

Increased Level of Angiopoietin Like Proteins 4 and 8 in People With Sleep Apnea
por: Al-Terki, Abdulmohsen, et al.
Publicado: (2018)

Association of COVID-19 Vaccines ChAdOx1-S and BNT162b2 with Circulating Levels of Coagulation Factors and Antithrombin
por: Hasan, Amal, et al.
Publicado: (2022)

ANGPTL4: A Predictive Marker for Diabetic Nephropathy
por: Al Shawaf, Eman, et al.
Publicado: (2019)

Interaction of Osteopontin with IL-18 in Obese Individuals: Implications for Insulin Resistance
por: Ahmad, Rasheed, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_fi2l6hvl7e0q0ddc3v2uu01gob