Mutation Types and Aging Differently Affect Revertant Fiber Expansion in Dystrophic Mdx and Mdx52 Mice

Duchenne muscular dystrophy (DMD), one of the most common and lethal genetic disorders, and the mdx mouse myopathies are caused by a lack of dystrophin protein. These dystrophic muscles contain sporadic clusters of dystrophin-expressing revertant fibers (RFs), as detected by immunohistochemistry. RF...

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Detalles Bibliográficos
Autores principales: Echigoya, Yusuke, Lee, Joshua, Rodrigues, Merryl, Nagata, Tetsuya, Tanihata, Jun, Nozohourmehrabad, Ashkan, Panesar, Dharminder, Miskew, Bailey, Aoki, Yoshitsugu, Yokota, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722172/
https://www.ncbi.nlm.nih.gov/pubmed/23894429
http://dx.doi.org/10.1371/journal.pone.0069194

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