Primary Respiratory Chain Disease Causes Tissue-Specific Dysregulation of the Global Transcriptome and Nutrient-Sensing Signaling Network

Primary mitochondrial respiratory chain (RC) diseases are heterogeneous in etiology and manifestations but collectively impair cellular energy metabolism. Mechanism(s) by which RC dysfunction causes global cellular sequelae are poorly understood. To identify a common cellular response to RC disease,...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Tsukikawa, Mai, Peng, Min, Polyak, Erzsebet, Nakamaru-Ogiso, Eiko, Ostrovsky, Julian, McCormack, Shana, Place, Emily, Clarke, Colleen, Reiner, Gail, McCormick, Elizabeth, Rappaport, Eric, Haas, Richard, Baur, Joseph A., Falk, Marni J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722174/
https://www.ncbi.nlm.nih.gov/pubmed/23894440
http://dx.doi.org/10.1371/journal.pone.0069282

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