Cargando…

Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells

Salinomycin is perhaps the first promising compound that was discovered through high throughput screening in cancer stem cells. This novel agent can selectively eliminate breast and other cancer stem cells, though the mechanism of action remains unclear. In this study, we found that salinomycin indu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Tianliang, Su, Ling, Zhong, Ning, Hao, Xuexi, Zhong, Diansheng, Singhal, Sunil, Liu, Xiangguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Basic Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722315/ https://www.ncbi.nlm.nih.gov/pubmed/23670030 http://dx.doi.org/10.4161/auto.24632

Ejemplares similares

Salermide up-regulates death receptor 5 expression through the ATF4-ATF3-CHOP axis and leads to apoptosis in human cancer cells
por: Liu, Guangbo, et al.
Publicado: (2012)

RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy
por: Luan, Qi, et al.
Publicado: (2015)

Salinomycin induces autophagic cell death in salinomycin-sensitive melanoma cells through inhibition of autophagic flux
por: Liu, Yajing, et al.
Publicado: (2020)

Salinomycin triggers endoplasmic reticulum stress through ATP2A3 upregulation in PC-3 cells
por: Zhang, Yunsheng, et al.
Publicado: (2019)

Abortive Autophagy Induces Endoplasmic Reticulum Stress and Cell Death in Cancer Cells
por: Claerhout, Sofie, et al.
Publicado: (2012)

Intracellular alpha-fetoprotein mitigates hepatocyte apoptosis and necroptosis by inhibiting endoplasmic reticulum stress
por: Chen, Yun-Fen, et al.
Publicado: (2022)

Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cells
por: Wang, Qilin, et al.
Publicado: (2012)

Salinomycin triggers prostate cancer cell apoptosis by inducing oxidative and endoplasmic reticulum stress via suppressing Nrf2 signaling
por: Yu, Jianyong, et al.
Publicado: (2021)

Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress
por: Hou, Xiao-Xue, et al.
Publicado: (2023)

Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis
por: Ren, Meng-Ting, et al.
Publicado: (2019)

Osthole induces apoptosis of the HT-29 cells via endoplasmic reticulum stress and autophagy
por: Zhou, Xing-Hua, et al.
Publicado: (2021)

Autophagy contributes to falcarindiol-induced cell death in breast cancer cells with enhanced endoplasmic reticulum stress
por: Lu, Tingting, et al.
Publicado: (2017)

Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats
por: Su, Wei, et al.
Publicado: (2020)

Effects of endoplasmic reticulum stress on erectile function in rats with cavernous nerve injury
por: Guo, Shanjie, et al.
Publicado: (2023)

Endoplasmic Reticulum Stress Signaling and Neuronal Cell Death
por: Merighi, Adalberto, et al.
Publicado: (2022)

Endoplasmic reticulum stress, cell death and tumor: Association between endoplasmic reticulum stress and the apoptosis pathway in tumors
por: Fu, Xiaojing, et al.
Publicado: (2021)

Yinchenhao decoction attenuates obstructive jaundice-induced liver injury and hepatocyte apoptosis by suppressing protein kinase RNA-like endoplasmic reticulum kinase-induced pathway
por: Wu, Yan-Li, et al.
Publicado: (2019)

Calpain-2 activity promotes aberrant endoplasmic reticulum stress-related apoptosis in hepatocytes
por: Xie, Ru-Jia, et al.
Publicado: (2020)

Effect of liraglutide on endoplasmic reticulum stress in the renal tissue of type 2 diabetic rats
por: Zhao, Xuan-Ye, et al.
Publicado: (2020)

Comprehensive analysis of endoplasmic reticulum stress-related mechanisms in type 2 diabetes mellitus
por: Liang, Bo, et al.
Publicado: (2023)

Glucose starvation-mediated inhibition of salinomycin induced autophagy amplifies cancer cell specific cell death
por: Jangamreddy, Jaganmohan R., et al.
Publicado: (2015)

Potential role of microRNA-503 in Icariin-mediated prevention of high glucose-induced endoplasmic reticulum stress
por: Su, Bao-Lin, et al.
Publicado: (2023)

The Novel Antitumor Compound HCA Promotes Glioma Cell Death by Inducing Endoplasmic Reticulum Stress and Autophagy
por: Beteta-Göbel, Roberto, et al.
Publicado: (2021)

New insights into the interplay between autophagy and oxidative and endoplasmic reticulum stress in neuronal cell death and survival
por: Gao, Yahao, et al.
Publicado: (2022)

Endoplasmic reticulum involvement in yeast cell death
por: Austriaco, O. P., Nicanor
Publicado: (2012)

The endoplasmic reticulum in plant immunity and cell death
por: Eichmann, Ruth, et al.
Publicado: (2012)

Role of endoplasmic reticulum stress in lipopolysaccharide-inhibited mouse granulosa cell estradiol production
por: LEI, Lanjie, et al.
Publicado: (2019)

Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death
por: Shibusawa, Ryo, et al.
Publicado: (2019)

Endoplasmic reticulum stress-mediated cell death in liver injury
por: Zhang, Jian, et al.
Publicado: (2022)

Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells
por: Quan, Wenying, et al.
Publicado: (2012)

Role of Autophagy in Cancer Cell Response to Nucleolar and Endoplasmic Reticulum Stress
por: Pecoraro, Annalisa, et al.
Publicado: (2020)

Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells
por: Moon, Seoil, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress and Allergic Diseases
por: Jeong, Jae Seok, et al.
Publicado: (2017)

Kaempferol induces hepatocellular carcinoma cell death via endoplasmic reticulum stress-CHOP-autophagy signaling pathway
por: Guo, Haiqing, et al.
Publicado: (2017)

4-Phenylbutyrate Prevents Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Heatstroke in the Intestines of Mice
por: Cao, Yan, et al.
Publicado: (2020)

Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure
por: Li, Wen-Yuan, et al.
Publicado: (2023)

Apoptosis, autophagy & endoplasmic reticulum stress in diabetes mellitus
por: Demirtas, Levent, et al.
Publicado: (2016)

Schistosoma japonicum attenuates dextran sodium sulfate-induced colitis in mice via reduction of endoplasmic reticulum stress
por: Liu, Ya, et al.
Publicado: (2017)

Irisin attenuates intestinal injury, oxidative and endoplasmic reticulum stress in mice with L-arginine-induced acute pancreatitis
por: Ren, Yi-Fan, et al.
Publicado: (2019)

Bortezomib initiates endoplasmic reticulum stress, elicits autophagy and death in Echinococcus granulosus larval stage
por: Nicolao, María Celeste, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_352k7hqr45v0h47n5srqcth66a