Cargando…

Revascularization surgery as a treatment concept for heart failure

Patients with heart failure symptoms due to ischemic cardiomyopathy face a poor prognosis without adequate treatment. In these patients with viable ischemic myocardium, revascularization surgery is not a new but an established treatment concept. the CASS study, published in 1983, was already able to...

Descripción completa

Detalles Bibliográficos
Autores principales: Ennker, J, Bauer, S, Ennker, I C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDIMES Edizioni Internazionali Srl 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722340/
https://www.ncbi.nlm.nih.gov/pubmed/23888231
_version_ 1782278179799433216
author Ennker, J
Bauer, S
Ennker, I C
author_facet Ennker, J
Bauer, S
Ennker, I C
author_sort Ennker, J
collection PubMed
description Patients with heart failure symptoms due to ischemic cardiomyopathy face a poor prognosis without adequate treatment. In these patients with viable ischemic myocardium, revascularization surgery is not a new but an established treatment concept. the CASS study, published in 1983, was already able to document the superiority of coronary artery revascularization in patients with poor left ventricular function. It is of utmost importance to predict regional functional recovery in order to assess viability and, thus, the indication for revascularization. Late gadoliniium enhancement cardiovascular magnetic resonance is the new gold standard. By applying this technique, it can be demonstrated that the transmural extent of a scar predicts segmental functional recovery. Numerous studies describe the predictors of survival of surgical revascularization, the indication and impact of medical antiarrhythmic treatment or choice of graft. In addition to conventional surgery, off-pump procedures, minimal extracorporeal circulation and hybrid revascularization have a special role in the treatment of patients with ischemic cardiomyopathy. Surgical techniques and medical therapies continue to improve. The future revascularization in these patients will focus on improving results and making coronary artery bypass grafting for elective revascularization less invasive and safer. Technical evolution, including the use of robotics and anastomotic connectors, intraoperative imaging and protein enzyme therapies, have to be defined concerning their special impact in these patients.
format Online
Article
Text
id pubmed-3722340
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher EDIMES Edizioni Internazionali Srl
record_format MEDLINE/PubMed
spelling pubmed-37223402013-07-25 Revascularization surgery as a treatment concept for heart failure Ennker, J Bauer, S Ennker, I C HSR Proc Intensive Care Cardiovasc Anesth Review-Article Patients with heart failure symptoms due to ischemic cardiomyopathy face a poor prognosis without adequate treatment. In these patients with viable ischemic myocardium, revascularization surgery is not a new but an established treatment concept. the CASS study, published in 1983, was already able to document the superiority of coronary artery revascularization in patients with poor left ventricular function. It is of utmost importance to predict regional functional recovery in order to assess viability and, thus, the indication for revascularization. Late gadoliniium enhancement cardiovascular magnetic resonance is the new gold standard. By applying this technique, it can be demonstrated that the transmural extent of a scar predicts segmental functional recovery. Numerous studies describe the predictors of survival of surgical revascularization, the indication and impact of medical antiarrhythmic treatment or choice of graft. In addition to conventional surgery, off-pump procedures, minimal extracorporeal circulation and hybrid revascularization have a special role in the treatment of patients with ischemic cardiomyopathy. Surgical techniques and medical therapies continue to improve. The future revascularization in these patients will focus on improving results and making coronary artery bypass grafting for elective revascularization less invasive and safer. Technical evolution, including the use of robotics and anastomotic connectors, intraoperative imaging and protein enzyme therapies, have to be defined concerning their special impact in these patients. EDIMES Edizioni Internazionali Srl 2013 /pmc/articles/PMC3722340/ /pubmed/23888231 Text en Copyright © 2013, HSR Proceedings in Intensive Care and Cardiovascular Anesthesia http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License 3.0, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/3.0/ and http://creativecommons.org/licenses/by-nc/3.0/legalcode.
spellingShingle Review-Article
Ennker, J
Bauer, S
Ennker, I C
Revascularization surgery as a treatment concept for heart failure
title Revascularization surgery as a treatment concept for heart failure
title_full Revascularization surgery as a treatment concept for heart failure
title_fullStr Revascularization surgery as a treatment concept for heart failure
title_full_unstemmed Revascularization surgery as a treatment concept for heart failure
title_short Revascularization surgery as a treatment concept for heart failure
title_sort revascularization surgery as a treatment concept for heart failure
topic Review-Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722340/
https://www.ncbi.nlm.nih.gov/pubmed/23888231
work_keys_str_mv AT ennkerj revascularizationsurgeryasatreatmentconceptforheartfailure
AT bauers revascularizationsurgeryasatreatmentconceptforheartfailure
AT ennkeric revascularizationsurgeryasatreatmentconceptforheartfailure