DMEAS: DNA methylation entropy analysis software

Summary: DMEAS is the first user-friendly tool dedicated to analyze the distribution of DNA methylation patterns for the quantification of epigenetic heterogeneity. It supports the analysis of both locus-specific and genome-wide bisulfite sequencing data. DMEAS progressively scans the mapping result...

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Autores principales: He, Jianlin, Sun, Xinxi, Shao, Xiaojian, Liang, Liji, Xie, Hehuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722522/
https://www.ncbi.nlm.nih.gov/pubmed/23749987
http://dx.doi.org/10.1093/bioinformatics/btt332
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author He, Jianlin
Sun, Xinxi
Shao, Xiaojian
Liang, Liji
Xie, Hehuang
author_facet He, Jianlin
Sun, Xinxi
Shao, Xiaojian
Liang, Liji
Xie, Hehuang
author_sort He, Jianlin
collection PubMed
description Summary: DMEAS is the first user-friendly tool dedicated to analyze the distribution of DNA methylation patterns for the quantification of epigenetic heterogeneity. It supports the analysis of both locus-specific and genome-wide bisulfite sequencing data. DMEAS progressively scans the mapping results of bisulfite sequencing reads to extract DNA methylation patterns for contiguous CpG dinucleotides. It determines the DNA methylation level and calculates methylation entropy for genomic segments to enable the quantitative assessment of DNA methylation variations observed in cell populations. Availability and implementation: DMEAS program, user guide and all the testing data are freely available from http://sourceforge.net/projects/dmeas/files/ Contact: davidxie@vt.edu Supplementary Information: Supplementary data are available at Bioinformatics online.
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spelling pubmed-37225222013-07-25 DMEAS: DNA methylation entropy analysis software He, Jianlin Sun, Xinxi Shao, Xiaojian Liang, Liji Xie, Hehuang Bioinformatics Applications Notes Summary: DMEAS is the first user-friendly tool dedicated to analyze the distribution of DNA methylation patterns for the quantification of epigenetic heterogeneity. It supports the analysis of both locus-specific and genome-wide bisulfite sequencing data. DMEAS progressively scans the mapping results of bisulfite sequencing reads to extract DNA methylation patterns for contiguous CpG dinucleotides. It determines the DNA methylation level and calculates methylation entropy for genomic segments to enable the quantitative assessment of DNA methylation variations observed in cell populations. Availability and implementation: DMEAS program, user guide and all the testing data are freely available from http://sourceforge.net/projects/dmeas/files/ Contact: davidxie@vt.edu Supplementary Information: Supplementary data are available at Bioinformatics online. Oxford University Press 2013-08-15 2013-06-08 /pmc/articles/PMC3722522/ /pubmed/23749987 http://dx.doi.org/10.1093/bioinformatics/btt332 Text en © The Author 2013. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
He, Jianlin
Sun, Xinxi
Shao, Xiaojian
Liang, Liji
Xie, Hehuang
DMEAS: DNA methylation entropy analysis software
title DMEAS: DNA methylation entropy analysis software
title_full DMEAS: DNA methylation entropy analysis software
title_fullStr DMEAS: DNA methylation entropy analysis software
title_full_unstemmed DMEAS: DNA methylation entropy analysis software
title_short DMEAS: DNA methylation entropy analysis software
title_sort dmeas: dna methylation entropy analysis software
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722522/
https://www.ncbi.nlm.nih.gov/pubmed/23749987
http://dx.doi.org/10.1093/bioinformatics/btt332
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AT xiehehuang dmeasdnamethylationentropyanalysissoftware

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