NOA: a cytoscape plugin for network ontology analysis

Summary: The Network Ontology Analysis (NOA) plugin for Cytoscape implements the NOA algorithm for network-based enrichment analysis, which extends Gene Ontology annotations to network links, or edges. The plugin facilitates the annotation and analysis of one or more networks in Cytoscape according...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Wang, Jiguang, Hanspers, Kristina, Xu, Dong, Chen, Luonan, Pico, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722524/
https://www.ncbi.nlm.nih.gov/pubmed/23749961
http://dx.doi.org/10.1093/bioinformatics/btt334
Descripción
Sumario:Summary: The Network Ontology Analysis (NOA) plugin for Cytoscape implements the NOA algorithm for network-based enrichment analysis, which extends Gene Ontology annotations to network links, or edges. The plugin facilitates the annotation and analysis of one or more networks in Cytoscape according to user-defined parameters. In addition to tables, the NOA plugin also presents results in the form of heatmaps and overview networks in Cytoscape, which can be exported for publication figures. Availability: The NOA plugin is an open source, Java program for Cytoscape version 2.8 available via the Cytoscape App Store (http://apps.cytoscape.org/apps/noa) and plugin manager. A detailed user manual is available at http://nrnb.org/tools/noa. Contact: apico@gladstone.ucsf.edu Supplementary information: Supplementary data are available at Bioinformatics online.

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