Liver FOXP3 and PD1/PDL1 Expression is Down-Regulated in Chronic HBV Hepatitis on Maintained Remission Related to the Degree of Inflammation

Background and Aim: T cell expression of PD1 and inhibition of T effector cells by Foxp3(+)-T regulatory cells are among the most powerful mechanisms for achieving a balanced immune response. Our aim was to investigate, how liver FOXP3 and PD1/PDL1 expression is regulated in chronic HBV hepatitis (C...

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Detalles Bibliográficos
Autores principales: Germanidis, Georgios, Argentou, Nikoletta, Hytiroglou, Prodromos, Vassiliadis, Themistoklis, Patsiaoura, Kalliopi, Germenis, Anastasios E., Speletas, Matthaios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722555/
https://www.ncbi.nlm.nih.gov/pubmed/23898331
http://dx.doi.org/10.3389/fimmu.2013.00207

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