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A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580
Important results were shown as cell survival points in the two panels of the figure which is reproduced in this Comment letter. A curve was fitted assuming the mono-exponential recovery half-time of 17 ± 21 minutes. The wide error limits indicate that this fit is not very good, but the notable feat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722597/ https://www.ncbi.nlm.nih.gov/pubmed/24310357 http://dx.doi.org/10.3390/cancers4041225 |
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author | Fowler, Jack F. |
author_facet | Fowler, Jack F. |
author_sort | Fowler, Jack F. |
collection | PubMed |
description | Important results were shown as cell survival points in the two panels of the figure which is reproduced in this Comment letter. A curve was fitted assuming the mono-exponential recovery half-time of 17 ± 21 minutes. The wide error limits indicate that this fit is not very good, but the notable feature of both panels is that the last four points are clearly continuing to rise, above the “fitted” curve. This indicates that there is a second, slower, component of repair or recovery and this Comment explores constructively the implications of that additional discovery. |
format | Online Article Text |
id | pubmed-3722597 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-37225972013-08-05 A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580 Fowler, Jack F. Cancers (Basel) Commentary Important results were shown as cell survival points in the two panels of the figure which is reproduced in this Comment letter. A curve was fitted assuming the mono-exponential recovery half-time of 17 ± 21 minutes. The wide error limits indicate that this fit is not very good, but the notable feature of both panels is that the last four points are clearly continuing to rise, above the “fitted” curve. This indicates that there is a second, slower, component of repair or recovery and this Comment explores constructively the implications of that additional discovery. MDPI 2012-11-22 /pmc/articles/PMC3722597/ /pubmed/24310357 http://dx.doi.org/10.3390/cancers4041225 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Commentary Fowler, Jack F. A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580 |
title | A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580 |
title_full | A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580 |
title_fullStr | A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580 |
title_full_unstemmed | A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580 |
title_short | A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580 |
title_sort | comment on qi et al.: an estimation of radiobiological parameters for head-and-neck and the clinical implications. cancers, 2012, 4, 566-580 |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722597/ https://www.ncbi.nlm.nih.gov/pubmed/24310357 http://dx.doi.org/10.3390/cancers4041225 |
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