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Polymerase chain reaction optimization for amplification of Guanine-Cytosine rich templates using buccal cell DNA
CONTEXT: Amplification of Guanine-Cytosine (GC) -rich sequences becomes important in screening and diagnosis of certain genetic diseases such as diseases arising due to expansion of GC-rich trinucleotide repeat regions. However, GC-rich sequences in the genome are refractory to standard polymerase c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722634/ https://www.ncbi.nlm.nih.gov/pubmed/23901197 http://dx.doi.org/10.4103/0971-6866.112898 |