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Subchondral Bone Regenerative Effect of Two Different Biomaterials in the Same Patient
This case report aims at highlighting the different effects on subchondral bone regeneration of two different biomaterials in the same patient, in addition to bone marrow derived cell transplantation (BMDCT) in ankle. A 15-year-old boy underwent a first BMDCT on a hyaluronate membrane to treat a dee...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722982/ https://www.ncbi.nlm.nih.gov/pubmed/23936705 http://dx.doi.org/10.1155/2013/850502 |
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author | Cavallo, Marco Buda, Roberto Vannini, Francesca Castagnini, Francesco Ruffilli, Alberto Giannini, Sandro |
author_facet | Cavallo, Marco Buda, Roberto Vannini, Francesca Castagnini, Francesco Ruffilli, Alberto Giannini, Sandro |
author_sort | Cavallo, Marco |
collection | PubMed |
description | This case report aims at highlighting the different effects on subchondral bone regeneration of two different biomaterials in the same patient, in addition to bone marrow derived cell transplantation (BMDCT) in ankle. A 15-year-old boy underwent a first BMDCT on a hyaluronate membrane to treat a deep osteochondral lesion (8 mm). The procedure failed: subchondral bone was still present at MRI. Two years after the first operation, the same procedure was performed on a collagen membrane with DBM filling the defect. After one year, AOFAS score was 100 points, and MRI showed a complete filling of the defect. The T2 mapping MRI after one year showed chondral tissue with values in the range of hyaline cartilage. In this case, DBM and the collagen membrane were demonstrated to be good biomaterials to restore subchondral bone: this is a critical step towards the regeneration of a healthy hyaline cartilage. |
format | Online Article Text |
id | pubmed-3722982 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37229822013-08-09 Subchondral Bone Regenerative Effect of Two Different Biomaterials in the Same Patient Cavallo, Marco Buda, Roberto Vannini, Francesca Castagnini, Francesco Ruffilli, Alberto Giannini, Sandro Case Rep Orthop Case Report This case report aims at highlighting the different effects on subchondral bone regeneration of two different biomaterials in the same patient, in addition to bone marrow derived cell transplantation (BMDCT) in ankle. A 15-year-old boy underwent a first BMDCT on a hyaluronate membrane to treat a deep osteochondral lesion (8 mm). The procedure failed: subchondral bone was still present at MRI. Two years after the first operation, the same procedure was performed on a collagen membrane with DBM filling the defect. After one year, AOFAS score was 100 points, and MRI showed a complete filling of the defect. The T2 mapping MRI after one year showed chondral tissue with values in the range of hyaline cartilage. In this case, DBM and the collagen membrane were demonstrated to be good biomaterials to restore subchondral bone: this is a critical step towards the regeneration of a healthy hyaline cartilage. Hindawi Publishing Corporation 2013 2013-07-07 /pmc/articles/PMC3722982/ /pubmed/23936705 http://dx.doi.org/10.1155/2013/850502 Text en Copyright © 2013 Marco Cavallo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Cavallo, Marco Buda, Roberto Vannini, Francesca Castagnini, Francesco Ruffilli, Alberto Giannini, Sandro Subchondral Bone Regenerative Effect of Two Different Biomaterials in the Same Patient |
title | Subchondral Bone Regenerative Effect of Two Different Biomaterials in the Same Patient |
title_full | Subchondral Bone Regenerative Effect of Two Different Biomaterials in the Same Patient |
title_fullStr | Subchondral Bone Regenerative Effect of Two Different Biomaterials in the Same Patient |
title_full_unstemmed | Subchondral Bone Regenerative Effect of Two Different Biomaterials in the Same Patient |
title_short | Subchondral Bone Regenerative Effect of Two Different Biomaterials in the Same Patient |
title_sort | subchondral bone regenerative effect of two different biomaterials in the same patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722982/ https://www.ncbi.nlm.nih.gov/pubmed/23936705 http://dx.doi.org/10.1155/2013/850502 |
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