Cargando…

LRP-1: A Checkpoint for the Extracellular Matrix Proteolysis

Low-density lipoprotein receptor-related protein-(LRP-1) is a large endocytic receptor that binds more than 35 ligands and exhibits signaling properties. Proteinases capable of degrading extracellular matrix (ECM), called matrix proteinases in this paper, are mainly serine proteinases: the activator...

Descripción completa

Detalles Bibliográficos
Autores principales:	Etique, Nicolas, Verzeaux, Laurie, Dedieu, Stéphane, Emonard, Hervé
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723059/ https://www.ncbi.nlm.nih.gov/pubmed/23936774 http://dx.doi.org/10.1155/2013/152163

Ejemplares similares

Intrinsic dynamics study identifies two amino acids of TIMP-1 critical for its LRP-1-mediated endocytosis in neurons
por: Verzeaux, Laurie, et al.
Publicado: (2017)

The Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor Environment
por: Van Gool, Bart, et al.
Publicado: (2015)

Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
por: Thevenard, Jessica, et al.
Publicado: (2014)

LRP-1 Promotes Cancer Cell Invasion by Supporting ERK and Inhibiting JNK Signaling Pathways
por: Langlois, Benoit, et al.
Publicado: (2010)

Cellular Cholesterol Distribution Influences Proteolytic Release of the LRP-1 Ectodomain
por: Dekky, Bassil, et al.
Publicado: (2016)

Identification of LRP-1 as an endocytosis and recycling receptor for β1-integrin in thyroid cancer cells
por: Theret, Louis, et al.
Publicado: (2017)

Editorial: Matricellular Receptors As Potential Targets in Anti-Cancer Therapeutic Strategies
por: Emonard, Hervé, et al.
Publicado: (2016)

LRP-1 Matricellular Receptor Involvement in Triple Negative Breast Cancer Tumor Angiogenesis
por: Campion, Océane, et al.
Publicado: (2021)

The Repertoire of Tissue Inhibitors of Metalloproteases: Evolution, Regulation of Extracellular Matrix Proteolysis, Engineering and Therapeutic Challenges
por: Costa, Salvatore, et al.
Publicado: (2022)

The extracellular matrix as an adhesion checkpoint for mammary epithelial function
por: Katz, Elad, et al.
Publicado: (2007)

Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2
por: Johanns, Manuel, et al.
Publicado: (2017)

Editorial: Neuroplasticity and Extracellular Proteolysis
por: Mozrzymas, Jerzy W., et al.
Publicado: (2016)

Inhibitory Effects of LRP1-Based Immunotherapy on Cardiac Extracellular Matrix Biophysical Alterations Induced by Hypercholesterolemia
por: Samouillan, Valerie, et al.
Publicado: (2023)

LRP-1 Promotes Colon Cancer Cell Proliferation in 3D Collagen Matrices by Mediating DDR1 Endocytosis
por: Le, Cao Cuong, et al.
Publicado: (2020)

LRP1 expression in colon cancer predicts clinical outcome
por: Boulagnon-Rombi, Camille, et al.
Publicado: (2018)

LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion
por: Langlois, Benoit, et al.
Publicado: (2022)

The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors
por: Boyé, Kevin, et al.
Publicado: (2017)

The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells
por: Henry, Aubery, et al.
Publicado: (2023)

Extracellular Proteolysis in Transgenic Mouse Models of Breast Cancer
por: Almholt, Kasper, et al.
Publicado: (2007)

Contribution of the Low-Density Lipoprotein Receptor Family to Breast Cancer Progression
por: Campion, Océane, et al.
Publicado: (2020)

Pericellular proteolysis in cancer
por: Sevenich, Lisa, et al.
Publicado: (2014)

The Role of Proteolysis in Amyloidosis
por: Acquasaliente, Laura, et al.
Publicado: (2022)

The NuRD Chromatin-Remodeling Enzyme CHD4 Promotes Embryonic Vascular Integrity by Transcriptionally Regulating Extracellular Matrix Proteolysis
por: Ingram, Kyle G., et al.
Publicado: (2013)

Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1
por: Martino-Echarri, Estefanía, et al.
Publicado: (2014)

Lrp4 Modulates Extracellular Integration of Cell Signaling Pathways in Development
por: Ohazama, Atsushi, et al.
Publicado: (2008)

KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae
por: Kanai, Yoshimitsu, et al.
Publicado: (2014)

Pulmonary Emphysema and Proteolysis
por: Sachs, Frederick L.
Publicado: (1974)

Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular, and intracellular events in matrix proteolysis by macrophages in culture
Publicado: (1980)

Proteomic Study of Fetal Membrane: Inflammation-Triggered Proteolysis of Extracellular Matrix May Present a Pathogenic Pathway for Spontaneous Preterm Birth
por: Pan, Jing, et al.
Publicado: (2020)

Proteolysis and inflammation of the kidney glomerulus
por: Demir, Fatih, et al.
Publicado: (2021)

Internal modulation of proteolysis in vascular extracellular matrix remodeling: role of ADAM metallopeptidase with thrombospondin type 1 motif 5 in the development of intracranial aneurysm rupture
por: Wang, Weihan, et al.
Publicado: (2021)

Low density lipoprotein receptors LRP-1 and LRP-2 in C. elegans
por: Minor, Paul J, et al.
Publicado: (2019)

EB1 Restricts Breast Cancer Cell Invadopodia Formation and Matrix Proteolysis via FAK
por: Chanez, Brice, et al.
Publicado: (2021)

Extracellular Matrix-Based and Electrospun Scaffolding Systems for Vaginal Reconstruction
por: Farzamfar, Saeed, et al.
Publicado: (2023)

LRP1B: A Giant Lost in Cancer Translation
por: Príncipe, Catarina, et al.
Publicado: (2021)

Extracellular proteolysis in structural and functional plasticity of mossy fiber synapses in hippocampus
por: Wiera, Grzegorz, et al.
Publicado: (2015)

Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis
por: Amor López, Ana, et al.
Publicado: (2021)

Extracellular Vesicles as Regulators of the Extracellular Matrix
por: Patel, Neil J., et al.
Publicado: (2023)

Complement C1q Interacts With LRP1 Clusters II and IV Through a Site Close but Different From the Binding Site of Its C1r and C1s-Associated Proteases
por: Fouët, Guillaume, et al.
Publicado: (2020)

LRP1B mutations are associated with favorable outcomes to immune checkpoint inhibitors across multiple cancer types
por: Brown, Landon C, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tvqd07ipn5on6s0f8goathu4fh