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Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice

Substantial evidence indicates an association between clinical depression and altered immune function. Systemic administration of bacterial lipopolysaccharide (LPS) is commonly used to study inflammation-associated behavioral changes in rodents. In these experiments, we tested the hypothesis that pe...

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Detalles Bibliográficos
Autores principales: Biesmans, Steven, Meert, Theo F., Bouwknecht, Jan A., Acton, Paul D., Davoodi, Nima, De Haes, Patrick, Kuijlaars, Jacobine, Langlois, Xavier, Matthews, Liam J. R., Ver Donck, Luc, Hellings, Niels, Nuydens, Rony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723093/
https://www.ncbi.nlm.nih.gov/pubmed/23935246
http://dx.doi.org/10.1155/2013/271359