Phosphorylation of Tau Protein as the Link between Oxidative Stress, Mitochondrial Dysfunction, and Connectivity Failure: Implications for Alzheimer's Disease

Alzheimer's disease (AD) is defined by the concurrence of abnormal aggregates composed of phosphorylated tau protein and of abnormal cellular changes including neurite degeneration, loss of neurons, and loss of cognitive functions. While a number of mechanisms have been implicated in this compl...

Descripción completa

Detalles Bibliográficos
Autores principales: Mondragón-Rodríguez, Siddhartha, Perry, George, Zhu, Xiongwei, Moreira, Paula I., Acevedo-Aquino, Mariana C., Williams, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723250/
https://www.ncbi.nlm.nih.gov/pubmed/23936615
http://dx.doi.org/10.1155/2013/940603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723250/
https://www.ncbi.nlm.nih.gov/pubmed/23936615
http://dx.doi.org/10.1155/2013/940603

Ejemplares similares