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Weaker control of the electrical properties of cerebellar granule cells by tonically active GABA(A) receptors in the Ts65Dn mouse model of Down’s syndrome
BACKGROUND: Down’s syndrome (DS) is caused by triplication of all or part of human chromosome 21 and is characterized by a decrease in the overall size of the brain. One of the brain regions most affected is the cerebellum, in which the number of granule cells (GCs) is markedly decreased. GCs proces...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723448/ https://www.ncbi.nlm.nih.gov/pubmed/23870245 http://dx.doi.org/10.1186/1756-6606-6-33 |