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Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans
Dietary restriction (DR) extends lifespan in a wide variety of species, yet the underlying mechanisms are not well understood. Here we show that the Caenorhabditis elegans HNF4α-related nuclear hormone receptor NHR-62 is required for metabolic and physiologic responses associated with DR-induced lon...
Autores principales: | Heestand, Bree N., Shen, Yidong, Liu, Wei, Magner, Daniel B., Storm, Nadia, Meharg, Caroline, Habermann, Bianca, Antebi, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723528/ https://www.ncbi.nlm.nih.gov/pubmed/23935515 http://dx.doi.org/10.1371/journal.pgen.1003651 |
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