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Chikungunya Virus Infection Results in Higher and Persistent Viral Replication in Aged Rhesus Macaques Due to Defects in Anti-Viral Immunity
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne Alphavirus that causes a clinical disease involving fever, myalgia, nausea and rash. The distinguishing feature of CHIKV infection is the severe debilitating poly-arthralgia that may persist for several months after viral clearance. Since its...
Autores principales: | Messaoudi, Ilhem, Vomaske, Jennifer, Totonchy, Thomas, Kreklywich, Craig N., Haberthur, Kristen, Springgay, Laura, Brien, James D., Diamond, Michael S., DeFilippis, Victor R., Streblow, Daniel N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723534/ https://www.ncbi.nlm.nih.gov/pubmed/23936572 http://dx.doi.org/10.1371/journal.pntd.0002343 |
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