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Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression

The large variability in mRNA and protein levels found from both static and dynamic measurements in single cells has been largely attributed to random periods of transcription, often occurring in bursts. The cell cycle has a pronounced global role in affecting transcriptional and translational outpu...

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Detalles Bibliográficos
Autores principales: Zopf, C. J., Quinn, Katie, Zeidman, Joshua, Maheshri, Narendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723585/
https://www.ncbi.nlm.nih.gov/pubmed/23935476
http://dx.doi.org/10.1371/journal.pcbi.1003161