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Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression
The large variability in mRNA and protein levels found from both static and dynamic measurements in single cells has been largely attributed to random periods of transcription, often occurring in bursts. The cell cycle has a pronounced global role in affecting transcriptional and translational outpu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723585/ https://www.ncbi.nlm.nih.gov/pubmed/23935476 http://dx.doi.org/10.1371/journal.pcbi.1003161 |