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The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity

To further its pathogenesis, S. Typhimurium delivers effector proteins into host cells, including the novel E3 ubiquitin ligase (NEL) effector SspH2. Using model systems in a cross-kingdom approach we gained further insight into the molecular function of this effector. Here, we show that SspH2 modul...

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Detalles Bibliográficos
Autores principales: Bhavsar, Amit P., Brown, Nat F., Stoepel, Jan, Wiermer, Marcel, Martin, Dale D. O., Hsu, Karolynn J., Imami, Koshi, Ross, Colin J., Hayden, Michael R., Foster, Leonard J., Li, Xin, Hieter, Phil, Finlay, B. Brett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723637/
https://www.ncbi.nlm.nih.gov/pubmed/23935490
http://dx.doi.org/10.1371/journal.ppat.1003518