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Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells
Disruption of pancreatic clock genes impairs pancreatic beta-cell function, leading to the onset of diabetes. Despite the importance of pancreatic alpha-cells in the regulation of glucose homeostasis and in diabetes pathophysiology, nothing is known about the role of clock genes in these cells. Here...
Autores principales: | Vieira, Elaine, Marroquí, Laura, Figueroa, Ana Lucia C., Merino, Beatriz, Fernandez-Ruiz, Rebeca, Nadal, Angel, Burris, Thomas P., Gomis, Ramon, Quesada, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723646/ https://www.ncbi.nlm.nih.gov/pubmed/23936124 http://dx.doi.org/10.1371/journal.pone.0069939 |
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