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Adaptor Proteins Intersectin 1 and 2 Bind Similar Proline-Rich Ligands but Are Differentially Recognized by SH2 Domain-Containing Proteins

BACKGROUND: Scaffolding proteins of the intersectin (ITSN) family, ITSN1 and ITSN2, are crucial for the initiation stage of clathrin-mediated endocytosis. These proteins are closely related but have implications in distinct pathologies. To determine how these proteins could be separated in certain c...

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Detalles Bibliográficos
Autores principales: Novokhatska, Olga, Dergai, Mykola, Tsyba, Liudmyla, Skrypkina, Inessa, Filonenko, Valeriy, Moreau, Jacques, Rynditch, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723668/
https://www.ncbi.nlm.nih.gov/pubmed/23936226
http://dx.doi.org/10.1371/journal.pone.0070546