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Efficient Sampling in Fragment-Based Protein Structure Prediction Using an Estimation of Distribution Algorithm
Fragment assembly is a powerful method of protein structure prediction that builds protein models from a pool of candidate fragments taken from known structures. Stochastic sampling is subsequently used to refine the models. The structures are first represented as coarse-grained models and then as a...
Autores principales: | Simoncini, David, Zhang, Kam Y. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723781/ https://www.ncbi.nlm.nih.gov/pubmed/23935913 http://dx.doi.org/10.1371/journal.pone.0068954 |
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