Prediction of Disease Causing Non-Synonymous SNPs by the Artificial Neural Network Predictor NetDiseaseSNP

We have developed a sequence conservation-based artificial neural network predictor called NetDiseaseSNP which classifies nsSNPs as disease-causing or neutral. Our method uses the excellent alignment generation algorithm of SIFT to identify related sequences and a combination of 31 features assessin...

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Detalles Bibliográficos
Autores principales: Johansen, Morten Bo, Izarzugaza, Jose M. G., Brunak, Søren, Petersen, Thomas Nordahl, Gupta, Ramneek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723835/
https://www.ncbi.nlm.nih.gov/pubmed/23935863
http://dx.doi.org/10.1371/journal.pone.0068370

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