Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening

Functionally interacting perturbations, such as synergistic drugs pairs or synthetic lethal gene pairs, are of key interest in both pharmacology and functional genomics. However, to find such pairs by traditional screening methods is both time consuming and costly. We present a novel computational-e...

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Detalles Bibliográficos
Autores principales: Gerlee, Philip, Schmidt, Linnéa, Monsefi, Naser, Kling, Teresia, Jörnsten, Rebecka, Nelander, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723843/
https://www.ncbi.nlm.nih.gov/pubmed/23935877
http://dx.doi.org/10.1371/journal.pone.0068598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723843/
https://www.ncbi.nlm.nih.gov/pubmed/23935877
http://dx.doi.org/10.1371/journal.pone.0068598

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