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Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening
Functionally interacting perturbations, such as synergistic drugs pairs or synthetic lethal gene pairs, are of key interest in both pharmacology and functional genomics. However, to find such pairs by traditional screening methods is both time consuming and costly. We present a novel computational-e...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723843/ https://www.ncbi.nlm.nih.gov/pubmed/23935877 http://dx.doi.org/10.1371/journal.pone.0068598 |