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The Peripheral Myeloid Expansion Driven by Murine Cancer Progression Is Reversed by Radiation Therapy of the Tumor
Expansion of myeloid-lineage leukocytes in tumor-bearing mice has been proposed as a cause of systemic immunosuppression. We demonstrate that radiation therapy of tumors leads to a decline in myeloid cell numbers in the blood and a decrease in spleen size. The frequency of myeloid cells does not dec...
Autores principales: | Crittenden, Marka R., Savage, Talicia, Cottam, Benjamin, Bahjat, Keith S., Redmond, William L., Bambina, Shelly, Kasiewicz, Melissa, Newell, Pippa, Jackson, Andrew M., Gough, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723876/ https://www.ncbi.nlm.nih.gov/pubmed/23936036 http://dx.doi.org/10.1371/journal.pone.0069527 |
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