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Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes

BACKGROUND: Excessive circular fatty acid, particlarly saturated fatty acid, can result in insulin resistance in skeletal muscle, but other adverse effects of fatty acid accumulation in myocytes remain unclear. METHODS: Differentiated C2C12 myotubes were used. The effects of palmitate on cell viabil...

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Detalles Bibliográficos
Autores principales:	Yang, Ming, Wei, Dandan, Mo, Chunfen, Zhang, Jie, Wang, Xu, Han, Xiaojuan, Wang, Zhe, Xiao, Hengyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723881/ https://www.ncbi.nlm.nih.gov/pubmed/23866690 http://dx.doi.org/10.1186/1476-511X-12-104

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