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A rapid & sensitive liquid chromatography- tandem mass spectrometry method for the quantitation of busulfan levels in plasma & application for routine therapeutic monitoring in haematopoietic stem cell transplantation

BACKGROUND & OBJECTIVES: Busulfan (Bu) in combination with cyclophosphamide is widely used in myeloablative conditioning regimen prior to haematopoietic stem cell transplantation (HSCT). Its narrow therapeutic range and toxic side effects at high systemic exposure and graft rejection at low expo...

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Detalles Bibliográficos
Autores principales:	Desire, Salamun, Mohanan, Ezhil Pavai, George, Biju, Mathews, Vikram, Chandy, Mammen, Srivastava, Alok, Balasubramanian, Poonkuzhali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724260/ https://www.ncbi.nlm.nih.gov/pubmed/23703347

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