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Purification and characterization of mutant miniPlasmin for thrombolytic therapy

BACKGROUND: Previous animal studies by us and others have indicated that catheter-administered plasmin or its des-kringle derivatives may be more appropriate alternatives to plasminogen activators for treating thrombolytic diseases, since it has a very short serum half-life and therefore does not re...

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Detalles Bibliográficos
Autores principales: Lin, Xiaotao, Wang, Yan, Zhang, Yanwen, Huang, Bing, Lin, James J, Hallock, Scott J, Yu, Hong, Shao, Hongwei, Yan, Jing, Huang, Bo, Zhang, Xuejun C, Cao, Wei, Xu, Xueming, Lin, Xinli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724493/
https://www.ncbi.nlm.nih.gov/pubmed/23363549
http://dx.doi.org/10.1186/1477-9560-11-2