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Acetaldehyde-Derived Advanced Glycation End-Products Promote Alcoholic Liver Disease

BACKGROUND: Chronic ingestion of ethanol increases acetaldehyde and leads to the production of acetaldehyde-derived advanced glycation end-products (AA-AGE). We evaluated the toxicity of AA-AGE on hepatocytes and studied the role of AA-AGE in the pathogenesis of alcoholic liver disease (ALD). METHOD...

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Detalles Bibliográficos
Autores principales:	Hayashi, Nobuhiko, George, Joseph, Takeuchi, Masayoshi, Fukumura, Atsushi, Toshikuni, Nobuyuki, Arisawa, Tomiyasu, Tsutsumi, Mikihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724722/ https://www.ncbi.nlm.nih.gov/pubmed/23922897 http://dx.doi.org/10.1371/journal.pone.0070034

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