In Vivo Administration of a JAK3 Inhibitor to Chronically SIV Infected Rhesus Macaques Leads to NK Cell Depletion Associated with Transient Modest Increase in Viral Loads

Innate immune responses are reasoned to play an important role during both acute and chronic SIV infection and play a deterministic role during the acute stages on the rate of infection and disease progression. NK cells are an integral part of the innate immune system but their role in influencing t...

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Detalles Bibliográficos
Autores principales: Takahashi, Yoshiaki, Mayne, Ann E., Khowawisetsut, Ladawan, Pattanapanyasat, Kovit, Little, Dawn, Villinger, Francois, Ansari, Aftab A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724739/
https://www.ncbi.nlm.nih.gov/pubmed/23923040
http://dx.doi.org/10.1371/journal.pone.0070992

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