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Suppression of Cytochrome P450 Reductase Enhances Long-Term Hematopoietic Stem Cell Repopulation Efficiency in Mice

BACKGROUND: Bone marrow microenvironment (niche) plays essential roles in the fate of hematopoietic stem cells (HSCs). Intracellular and extracellular redox metabolic microenvironment is one of the critical factors for the maintenance of the niche. Cytochrome P450 reductase (CPR) is an obligate elec...

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Detalles Bibliográficos
Autores principales:	Zhang, Yan, Dong, Fang, Zhang, Na, Cheng, Hui, Pang, Yakun, Wang, Xiaomin, Xu, Jing, Ding, Xinxin, Cheng, Tao, Gu, Jun, Yuan, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724780/ https://www.ncbi.nlm.nih.gov/pubmed/23922855 http://dx.doi.org/10.1371/journal.pone.0069913

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