Cargando…
The LDL Receptor-Related Protein 1 (LRP1) Regulates the PDGF Signaling Pathway by Binding the Protein Phosphatase SHP-2 and Modulating SHP-2- Mediated PDGF Signaling Events
BACKGROUND: The PDGF signaling pathway plays a major role in several biological systems, including vascular remodeling that occurs following percutaneous transluminal coronary angioplasty. Recent studies have shown that the LDL receptor-related protein 1 (LRP1) is a physiological regulator of the PD...
Autores principales: | Craig, Julie, Mikhailenko, Irina, Noyes, Nathaniel, Migliorini, Mary, Strickland, Dudley K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724782/ https://www.ncbi.nlm.nih.gov/pubmed/23922991 http://dx.doi.org/10.1371/journal.pone.0070432 |
Ejemplares similares
-
LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages
por: Lillis, Anna P., et al.
Publicado: (2015) -
Correction: LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages
por: Lillis, Anna P., et al.
Publicado: (2016) -
Inhibition of SHP2 and SHP1 Protein Tyrosine Phosphatase
Activity by Chemically Induced Dimerization
por: Buck, Sara J. S., et al.
Publicado: (2022) -
Destabilization of the SHP2 and SHP1 protein tyrosine phosphatase domains by a non-conserved “backdoor” cysteine
por: Yarnall, Matthew T.N., et al.
Publicado: (2022) -
SHP-2-Induced Activation of c-Myc Is Involved in PDGF-B-Regulated Cell Proliferation and Angiogenesis in RMECs
por: Ma, Jun, et al.
Publicado: (2020)