Cargando…
Secreted Acid Phosphatase (SapM) of Mycobacterium tuberculosis Is Indispensable for Arresting Phagosomal Maturation and Growth of the Pathogen in Guinea Pig Tissues
Tuberculosis (TB) is responsible for nearly 1.4 million deaths globally every year and continues to remain a serious threat to human health. The problem is further complicated by the growing incidence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB), emphasizing the need...
Autores principales: | Puri, Rupangi Verma, Reddy, P. Vineel, Tyagi, Anil K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724783/ https://www.ncbi.nlm.nih.gov/pubmed/23923000 http://dx.doi.org/10.1371/journal.pone.0070514 |
Ejemplares similares
-
Apurinic/Apyrimidinic Endonucleases of Mycobacterium tuberculosis Protect against DNA Damage but Are Dispensable for the Growth of the Pathogen in Guinea Pigs
por: Puri, Rupangi Verma, et al.
Publicado: (2014) -
Discovery of uncompetitive inhibitors of SapM that compromise intracellular survival of Mycobacterium tuberculosis
por: Fernández-Soto, Paulina, et al.
Publicado: (2021) -
Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs
por: Fernandez-Soto, Paulina, et al.
Publicado: (2019) -
Secretory Phosphatases Deficient Mutant of Mycobacterium tuberculosis Imparts Protection at the Primary Site of Infection in Guinea Pigs
por: Chauhan, Priyanka, et al.
Publicado: (2013) -
The fbpA/sapM Double Knock Out Strain of Mycobacterium tuberculosis Is Highly Attenuated and Immunogenic in Macrophages
por: Saikolappan, Sankaralingam, et al.
Publicado: (2012)