E- and P-Selectins Are Essential for Repopulation of Chronic Myelogenous and Chronic Eosinophilic Leukemias in a Scid Mouse Xenograft Model

In chronic myelogenous (CML) and chronic eosinophilic leukemia (CEL), neoplastic cells spread via the circulation into various extramedullary organs. As E- and P-selectin constitute the starting point for the leucocyte adhesion/invasion cascade, and CEL and CML cells share many properties with norma...

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Detalles Bibliográficos
Autores principales: Wicklein, Daniel, Schmidt, Anna, Labitzky, Vera, Ullrich, Sebastian, Valent, Peter, Schumacher, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724803/
https://www.ncbi.nlm.nih.gov/pubmed/23922938
http://dx.doi.org/10.1371/journal.pone.0070139

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