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Celecoxib Ameliorates Portal Hypertension of the Cirrhotic Rats through the Dual Inhibitory Effects on the Intrahepatic Fibrosis and Angiogenesis
BACKGROUND: Increased intra-hepatic resistance to portal blood flow is the primary factor leading to portal hypertension in cirrhosis. Up-regulated expression of cyclooxygenase-2 (COX-2) in the cirrhotic liver might be a potential target to ameliorate portal hypertension. OBJECTIVE: To verify the ef...
Autores principales: | Gao, Jin-Hang, Wen, Shi-Lei, Yang, Wen-Juan, Lu, Yao-Yao, Tong, Huan, Huang, Zhi-Yin, Liu, Zhang-Xu, Tang, Cheng-Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724827/ https://www.ncbi.nlm.nih.gov/pubmed/23922700 http://dx.doi.org/10.1371/journal.pone.0069309 |
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