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Development of a Nuclear Morphometric Signature for Prostate Cancer Risk in Negative Biopsies
BACKGROUND: Our objective was to develop and validate a multi-feature nuclear score based on image analysis of direct DNA staining, and to test its association with field effects and subsequent detection of prostate cancer (PCa) in benign biopsies. METHODS: Tissue sections from 39 prostatectomies we...
Autores principales: | Gann, Peter H., Deaton, Ryan, Amatya, Anup, Mohnani, Mahesh, Rueter, Erika Enk, Yang, Yirong, Ananthanarayanan, Viju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724855/ https://www.ncbi.nlm.nih.gov/pubmed/23922715 http://dx.doi.org/10.1371/journal.pone.0069457 |
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