Propyl-2-(8-(3,4-Difluorobenzyl)-2′,5′-Dioxo-8-Azaspiro[Bicyclo[3.2.1] Octane-3,4′-Imidazolidine]-1′-yl) Acetate Induces Apoptosis in Human Leukemia Cells through Mitochondrial Pathway following Cell Cycle Arrest

BACKGROUND: Due to the functional defects in apoptosis signaling molecules or deficient activation of apoptosis pathways, leukemia has become an aggressive disease with poor prognosis. Although the majority of leukemia patients initially respond to chemotherapy, relapse is still the leading cause of...

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Detalles Bibliográficos
Autores principales: Kavitha, Chandagirikoppal V., Nambiar, Mridula, Narayanaswamy, Pavan B., Thomas, Elizabeth, Rathore, Ujjwal, Ananda Kumar, Channapillekoppalu S., Choudhary, Bibha, Rangappa, Kanchugarakoppal S., Raghavan, Sathees C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724874/
https://www.ncbi.nlm.nih.gov/pubmed/23922684
http://dx.doi.org/10.1371/journal.pone.0069103

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