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Dimerization of the Glucan Phosphatase Laforin Requires the Participation of Cysteine 329
Laforin, encoded by a gene that is mutated in Lafora Disease (LD, OMIM 254780), is a modular protein composed of a carbohydrate-binding module and a dual-specificity phosphatase domain. Laforin is the founding member of the glucan-phosphatase family and regulates the levels of phosphate present in g...
Autores principales: | Sánchez-Martín, Pablo, Raththagala, Madushi, Bridges, Travis M., Husodo, Satrio, Gentry, Matthew S., Sanz, Pascual, Romá-Mateo, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724922/ https://www.ncbi.nlm.nih.gov/pubmed/23922729 http://dx.doi.org/10.1371/journal.pone.0069523 |
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