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Adaptive and Specialised Transcriptional Responses to Xenobiotic Stress in Caenorhabditis elegans Are Regulated by Nuclear Hormone Receptors
Characterisation of the pathways by which xenobiotics are metabolised and excreted in both target and non-target organisms is crucial for the rational design of effective and specific novel bioactive molecules. Consequently, we have investigated the induced responses of the model nematode Caenorhabd...
Autores principales: | Jones, Laura M., Rayson, Samantha J., Flemming, Anthony J., Urwin, Peter E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724934/ https://www.ncbi.nlm.nih.gov/pubmed/23922869 http://dx.doi.org/10.1371/journal.pone.0069956 |
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