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Computational modeling of the p7 monomer from HCV and its interaction with small molecule drugs

Hepatitis C virus p7 protein is a 63 amino acid polytopic protein with two transmembrane domains (TMDs) and one of the prime targets for anti HCV drug development. A bio-inspired modeling pathway is used to generate plausible computational models of the two TMDs forming the monomeric protein model....

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Detalles Bibliográficos
Autores principales: Wang, Yi-Ting, Hsu, Hao-Jen, Fischer, Wolfgang B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724979/
https://www.ncbi.nlm.nih.gov/pubmed/23961398
http://dx.doi.org/10.1186/2193-1801-2-324