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A gene expression profile indicative of early stage HER2 targeted therapy response

BACKGROUND: Efficacious application of HER2-targetting agents requires the identification of novel predictive biomarkers. Lapatinib, afatinib and neratinib are tyrosine kinase inhibitors (TKIs) of HER2 and EGFR growth factor receptors. A panel of breast cancer cell lines was treated with these agent...

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Detalles Bibliográficos
Autores principales:	O’Neill, Fiona, Madden, Stephen F, Clynes, Martin, Crown, John, Doolan, Padraig, Aherne, Sinéad T, O’Connor, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725168/ https://www.ncbi.nlm.nih.gov/pubmed/23816254 http://dx.doi.org/10.1186/1476-4598-12-69

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