Celiac Disease and Autoimmunity: Review and Controversies

Celiac disease (CD) is an autoimmune condition affecting the small intestine, triggered by the ingestion of gluten, the protein fraction of wheat, barley, and rye. There is a strong linkage between CD and HLA-DQ2 and HLA-DQ8 haplotypes. Multiple case reports and small series suggest concordance betw...

Descripción completa

Detalles Bibliográficos
Autores principales: Denham, Jolanda M., Hill, Ivor D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Autoimmunity (Tk Tarrant, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725235/
https://www.ncbi.nlm.nih.gov/pubmed/23681421
http://dx.doi.org/10.1007/s11882-013-0352-1
_version_ 1782476777616048128
author Denham, Jolanda M.
Hill, Ivor D.
author_facet Denham, Jolanda M.
Hill, Ivor D.
author_sort Denham, Jolanda M.
collection PubMed
description Celiac disease (CD) is an autoimmune condition affecting the small intestine, triggered by the ingestion of gluten, the protein fraction of wheat, barley, and rye. There is a strong linkage between CD and HLA-DQ2 and HLA-DQ8 haplotypes. Multiple case reports and small series suggest concordance between CD and other autoimmune disorders. This paper provides a brief overview of the pathogenesis of CD and reviews the literature regarding associations between CD and other autoimmune diseases, including the potential effects of gluten-free diet therapy on the prevention or amelioration of associated diseases.
format Online
Article
Text
id pubmed-3725235
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-37252352013-08-01 Celiac Disease and Autoimmunity: Review and Controversies Denham, Jolanda M. Hill, Ivor D. Curr Allergy Asthma Rep Autoimmunity (Tk Tarrant, Section Editor) Celiac disease (CD) is an autoimmune condition affecting the small intestine, triggered by the ingestion of gluten, the protein fraction of wheat, barley, and rye. There is a strong linkage between CD and HLA-DQ2 and HLA-DQ8 haplotypes. Multiple case reports and small series suggest concordance between CD and other autoimmune disorders. This paper provides a brief overview of the pathogenesis of CD and reviews the literature regarding associations between CD and other autoimmune diseases, including the potential effects of gluten-free diet therapy on the prevention or amelioration of associated diseases. Springer US 2013-05-17 2013 /pmc/articles/PMC3725235/ /pubmed/23681421 http://dx.doi.org/10.1007/s11882-013-0352-1 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by-nc/2.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Autoimmunity (Tk Tarrant, Section Editor)
Denham, Jolanda M.
Hill, Ivor D.
Celiac Disease and Autoimmunity: Review and Controversies
title Celiac Disease and Autoimmunity: Review and Controversies
title_full Celiac Disease and Autoimmunity: Review and Controversies
title_fullStr Celiac Disease and Autoimmunity: Review and Controversies
title_full_unstemmed Celiac Disease and Autoimmunity: Review and Controversies
title_short Celiac Disease and Autoimmunity: Review and Controversies
title_sort celiac disease and autoimmunity: review and controversies
topic Autoimmunity (Tk Tarrant, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725235/
https://www.ncbi.nlm.nih.gov/pubmed/23681421
http://dx.doi.org/10.1007/s11882-013-0352-1
work_keys_str_mv AT denhamjolandam celiacdiseaseandautoimmunityreviewandcontroversies
AT hillivord celiacdiseaseandautoimmunityreviewandcontroversies

Ejemplares similares