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NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons

Thanks to the development of efficient differentiation strategies, human pluripotent stem cells (HPSC) offer the opportunity for modelling neuronal injury and dysfunction in human neurons in vitro. Critically, the effective use of HPSC-derived neural cells in disease-modelling and potentially cell r...

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Detalles Bibliográficos
Autores principales: Gupta, Kunal, Hardingham, Giles E., Chandran, Siddharthan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725411/
https://www.ncbi.nlm.nih.gov/pubmed/23518152
http://dx.doi.org/10.1016/j.neulet.2013.03.010